Antiprotozoal drugs

Antiprotozoal drugs

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Helicobacter pylori

Metronidazole, a nitroimidazole that also kills protozoa, is a common partner.

  • PenicillinsAntimicrobials and chemotherapeuticsAmoxicillin is a mainstay of eradication regimens.
  • Macrolides and ketolides (50S inhibitors)Antimicrobials and chemotherapeuticsClarithromycin is used where resistance to it is low.
  • Tetracyclines (30S inhibitors)Antimicrobials and chemotherapeuticsTetracycline is part of bismuth quadruple therapy.
  • Antiulcer drugsGastrointestinal, metabolic and hormonal drugsNot written yetEvery regimen has an acid blocker, usually a proton pump inhibitor; bismuth is added in bismuth quadruple therapy.
  • Helicobacter pylori infectionInternal medicineNot written yetHow the infection is found and eradicated.
  • Peptic ulcerInternal medicineNot written yetIt causes most duodenal and many gastric ulcers; eradication largely stops them coming back.
  • Gastric carcinomaInternal medicineNot written yetLong infection raises the risk of gastric adenocarcinoma.
  • Non-Hodgkin’s lymphomasInternal medicineGastric MALT lymphoma can regress once the bacterium is eradicated.